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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Inhibition of EZH2 by chidamide exerts antileukemia activity and increases chemosensitivity through Smo/Gli-1 pathway in acute myeloid leukemia

Fig. 1

Chidamide suppresses growth and induces apoptosis in AML cells and stem/progenitor cells. a Kasumi-1 and HL-60/ADM cells were treated with chidamide for 24, 48 and 72 h. Cell viability was assessed with CCK-8. b Kasumi-1 and HL-60/ADM cells were treated with chidamide for 48 h. Apoptosis was determined by flow cytometry. c Patient samples were treated with chidamide for 48 h. Apoptosis in CD45 + and CD34 + CD38- cells was measured by flow cytometry. *P < 0.05: **P < 0.01

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