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Table 2 Taxonomic identification at the phylum and genus levels in COPD

From: Association of exacerbation phenotype with the sputum microbiome in chronic obstructive pulmonary disease patients during the clinically stable state

Phylum LRE HRE p value PFT I PFT II p value
Patients 60 18   43 35  
Firmicutes 54.59 (41.54–73.32) 43.50 (31.63–60.68) 0.075 48.32 (40–66.09) 57.67 (38.70–69.2) 0.605
Actinobacteria 16.63 (8.48–28.24) 16.71 (11.58–22.79) 0.652 17.08 (8.62–27.99) 15.19 (10.11–24.00) 0.591
Proteobacteria 10.87 (1.69–22.06) 22.28 (8.70–37.70) 0.031 12.66 (1.90–21.82) 11.25 (5.96–24.55) 0.289
Bacteroidetes 3.26 (0.87–6.47) 3.98 (0.27–12.59) 0.610 3.51 (1.22–7.41) 3.18 (0.58–7.55) 0.706
Fusobacteria 2.00 (0.88–4.57) 2.95 (0.57–4.73) 0.585 2.36 (1.04–4.95) 1.65 (0.84–3.44) 0.083
Genera
 Streptococcus 41.24 (28.72–60.15) 28.68 (22.91–35.54) 0.007 39.94 (28.61–60.65) 34.83 (25.70–49.55) 0.226
 Rothia 10.83 (4.31–18.67) 10.20 (4.82–21.14) 0.859 10.86 (4.50–19.53) 10.51 (3.96–16.65) 0.543
 Neisseria 3.07 (0.34–10.51) 3.42 (0.82–11.06) 0.400 3.04 (0.39–9.95) 4.21 (0.31–13.13) 0.393
 Haemophilus 2.72 (0.19–6.43) 1.34 (0.22–11.76) 0.962 3.21 (0.23–6.41) 2.38 (0.16–11.69) 0.868
 Granulicatella 2.54 (1.57–3.93) 2.95 (1.71–5.54) 0.343 2.54 (1.33–3.64) 2.86 (1.77–4.39) 0.317
 Veillonella 1.45 (0.73–3.19) 2.25 (0.69–5.25) 0.226 1.73 (0.71–4.11) 1.64 (0.89–3.48) 0.956
 Leptotrichia 1.30 (0.42–2.67) 1.14 (0.32–3.62) 0.840 1.67 (0.49–3.51) 0.96 (0.36–2.60) 0.353
 Porphyromonas 0.96 (0.03–3.29) 0.94 (0.04–4.50) 0.677 1.03 (0.05–3.39) 0.78 (0.02–3.02) 0.790
 Actinomyces 0.55 (0.19–1.35) 0.92 (0.34–1.48) 0.215 0.82 (0.19–1.43) 0.50 (0.25–1.26) 0.802
 Capnocytophaga 0.37 (0.06–1.58) 0.61 (0.08–1.88) 0.585 0.46 (0.09–1.73) 0.42 (0.04–1.19) 0.457
  1. Data are presented as median (25–75 percentile)
  2. LRE low risk exacerbator, HRE high risk exacerbator, PFT pulmonary function test, PFT I FEV1 ≥ 50, PFT II FEV1 < 50.0
  3. The p value is analyzed using Mann Whitney Wilcoxon test. Bonferroni-adjusted p-values < 0.05/15 (5 phylum and 10 genus) = 0.0033 indicate significance