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Table 2 Univariate and multivariate analyses of different prognostic factors in 90 patients with HCC

From: CMTM6 promotes migration, invasion, and EMT by interacting with and stabilizing vimentin in hepatocellular carcinoma cells

Features Univariate analysis Multivariate analysis
HR (95% CI) P-value HR (95% CI) P-value
Age (years; < 60 vs. ≥ 60) 1.298 (0.600–2.807) 0.508  
Sex (male vs. female) 0.520 (0.124–2.176) 0.371  
Microvascular invasion (absent vs. present) 2.476 (1.162–5.277) 0.019*  
Tumour size (cm; < 5 vs. ≥ 5) 1.928 (0.952–3.904) 0.068  
Differentiation (well, moderate, poor) 2.160 (1.218–3.830) 0.008* 0.514 (0.309–0.856) 0.011*
HBsAg (positive vs. negative) 1.270 (0.516–3.124) 0.603  
AFP (< 25 vs. ≥ 25) 1.607 (0.770–3.356) 0.206  
TNM stage (I + II vs. III + IV) 2.425 (1.088–5.407) 0.030*  
Expression of CMTM6 (low vs. high) 2.427 (0.997–5.906) 0.041* 2.816 (1.118–7.096) 0.006*
Expression of vimentin (low vs. high) 2.245 (1.007–5.005) 0.048* 3.196 (1.391–7.340) 0.037*
Co-expression
 CMTM6 (high) vimentin (high)
 CMTM6 (high) vimentin (low)
 CMTM6 (low) vimentin (high)
 CMTM6 (low) vimentin (low)
0.716 (0.519–0.987) 0.042* 1.796 (0.826–3.908) 0.040*
  1. * p < 0.05