Hand grip strength and fatigability: correlation with clinical parameters and diagnostic suitability in ME/CFS

Table 4 Clinical characteristics of ME/CFS and correlations with handgrip strength

PEM	Median	Range	n	Median	Range	n
PEM	37	9–46	35	34	21–46	35
Correlations	r	p	type	r	p	Type
Fmean2	− 0.334	0.0499	non-lin	− 0.1987	0.2526	non-lin
Fatigue Ratio2	0.4040	0.0161	lin	0.34	0.0457	lin

Muscle Pain	Median	Range	n	Median	Range	n
Muscle Pain	8	0–10	50	6	1–10	39
Correlations	r	p	type	r	p	Type
Fmean2	− 0.3095	0.0287	lin	− 0.1643	0.3175	lin
Recovery Ratio	− 0.282	0.0472	non-lin	− 0.1542	0.3488	non-lin

COMPASS vasomotor	Median	Range	n	Median	Range	n
COMPASS vasomotor	0	0–5	49	0	0–5	40
Correlations	r	p	Type	r	p	Type
Fmax1	− 0.2664	0.0643	non-lin	− 0.3537	0.0251	non-lin
Fmax2	− 0.3635	0.0102	non-lin	− 0.4327	0.0026	non-lin
Fmean1	− 0.3013	0.0354	non-lin	− 0.3784	0.0161	non-lin
Fmean2	− 0.3663	0.0096	non-lin	− 0.5767	< 0.0001	non-lin
Fatigue Ratio2	0.03817	0.7946	lin	0.4869	0.0014	lin
Recovery Ratio	− 0.1938	0.1821	non-lin	− 0.628	< 0.0001	non-lin

SF-36 phys. funct	Median	Range	n	Median	Range	n
SF-36 phys. funct	40	5–90	52	47.5	0–100	38
Correlations	r	p	Type	r	p	Type
Fmax2	0.1724	0.2217	non-lin	0.3474	0.0351	non-lin
Fmean2	0.2326	0.0970	lin	0.3605	0.0284	lin

CK	Median	Range	n	Median	Range	n
CK	67.5	15–229	48	90	29–447	33
Correlations	r	p	Type	r	p	Type
Fatigue Ratio2	0.3054	0.0348	lin	− 0.1856	0.3092	lin
Recovery Ratio	− 0.2935	0.0429	lin	− 0.1045	0.5691	lin

LDH	Median	Range	n	Median	Range	n
LDH	216	150–286	47	225.5	145–308	34
Correlations	r	p	Type	r	p	Type
Fatigue Ratio1	− 0.06696	0.6547	non-lin	0.3522	0.0411	non-lin
Fatigue Ratio2	0.3630	0.0122	non-lin	0.2683	0.125	non-lin
Recovery Ratio	− 0.0336	0.8226	non-lin	− 0.378	0.0275	non-lin

Clinical parameters with significant correlations with HGS and HGS ratios. Pearson (lin) or Spearman (non-lin) correlation coefficients were calculated. Bold: significant correlations with p < 0.05

ISSN: 1479-5876