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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Hand grip strength and fatigability: correlation with clinical parameters and diagnostic suitability in ME/CFS

Fig. 1

Handgrip strength (a), Fmax (b) and Fmean (c). ME/CFS patients showed lower levels and stronger decrease of HGS compared to HC over ten repeat pulls resulting in significantly diminished Fmax and Fmean in the patient group. Further, Fmax and Fmean dropped significantly after one hour in ME/CFS as well as in CRF patients, whereas it remains unchanged in healthy women or even raised in healthy men. Ten repeat measurements of maximal HGS were performed in two sessions (60-mininterval) by a hand dynamometer (in kg). Left: female ME/CFS patients (circles, n = 61), CFR patients (triangles, n = 18) and HC (squares, n = 36); right: male ME/CFS patients (circles, n = 44) and (HC, (squares, n = 30). Continuous line: initial session, dotted line: second session after one hour. Boxplots 10–90 percentile with outliers, ns = p > 0.05, *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 (Mann–Whitney-Test for comparison between groups, paired-t-test for comparison of both sessions). Mean values in kg with SD

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