Fig. 4

a The radar plot exhibits several GO biological pathways that were significantly enriched in multiple cancer types based on the invasiveness-related DEGs. The number of cancers of each biological pathway is shown as the position of the corresponding dot in each spoke. b Correlation between the invasiveness score and the ssGSEA score of several pathways, as well as the mutation load, across 30 cancer types. Dot size is proportional to the −log P-value of correlation; color indicates magnitude of correlation (r value). c Comparison of the 4 immune-checkpoint molecules’ expression level in high- and low-invasiveness group across multiple cancer types. The points connected by lines represent the mean value of the expression level in each group across different cancer types, whereas the significantly differential expression is annotated with a red dot on the top of plot. Dot size are proportional to the −log P-value of t-test