Fig. 1

a Spearman’s correlation of the invasiveness score between this 24-gene signature and the other two gene signatures across 30 cancer types. b The distribution of the invasiveness score across 30 cancer types. Within each group, the scattered dots represent the invasiveness score of each patient. The lines in the boxes represents the median value. The bottom and top of the boxes are the 25th and 75th percentiles (interquartile range). The whiskers encompass 1.5 times the interquartile range. c Kaplan–Meier curves shows that high-invasiveness score group is associated with worse RFS in LUAD, LUSC, and ESCA cohort. d The prognostic value of invasiveness score in each cancer type, shown in the forest plot with corresponding hazard ratio (HR) and 95% confident interval (95% CI). e Gene set enrichment analysis (GSEA) based on mass proteomic spectrum data indicated that the proteins in the invasiveness-signature were significantly enriched in the high-invasiveness score group in BRCA and OV