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Table 4 Adverse effects (any grades) of immune checkpoint inhibitors after pemetrexed treatment failure

From: High lymphocyte population-related predictive factors for a long-term response in non-small cell lung cancer patients treated with pemetrexed: a retrospective observational study

Adverse effects

Long-term

administration

( n = 11)

Intermediate-term

administration

( n = 16)

Short-term

administration

( n = 55)

irAE

5 (45.5%) *

3 (18.8%)

10 (18.2%)

ILD

4 (36.3%)

2 (12.5%)

2 (3.6%)

Others

1 (9.1%)

1 (6.3%)

9 (16.4%)

  1. irAE immune-related adverse events, ILD interstitial lung disease
  2. *: P < 0.05 (Chi-square test)