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Table 2 Logistic regression analysis for prognostic factors of long-term (17 courses) response of pemetrexed

From: High lymphocyte population-related predictive factors for a long-term response in non-small cell lung cancer patients treated with pemetrexed: a retrospective observational study

Characteristics Univariate analysis Multivariate analysis
P value Hazard ratio
(95%CI)
P value Hazard ratio
(95%CI)
Age 0.006* 1.067 (1.018–1.118) 0.027* 1.068 (1.007–1.132)
Sex 0.588 0.797 (0.351–1.810) 0.125 0.413 (0.133–1.279)
ECOG PS 0.228 3.485 (0.457–26.580) 0.459 0.441 (0.051–3.851)
Smoking history 0.425 0.691 (0.279–1.713) 0.261 0.492 (0.143–1.694)
Stage (8th edition) 0.013* 0.656 (0.470–0.914) 0.030* 0.666 (0.461–0.962)
Therapy line 0.630 1.232 (0.526–2.887) 0.876 0.918 (0.313–2.690)
Platinum combination 0.463 1.378 (0.585–3.247) 0.764 0.841 (0.272–2.604)
Neutrophils (/mm2) 0.228 1.000 (1.000–1.000) 0.041* 1.000 (0.999–1.000)
Lymphocytes (/mm2) 0.020* 1.000 (1.000–1.001) 0.033* 1.001 (1.000–1.001)
Monocytes (/mm2) 0.337 1.001 (0.999–1.003) 0.016* 1.001 (1.001–1.007)
NLR 0.023* 0.693 (0.505–0.951)
  1. ALC absolute lymphocyte count (/mm3), ECOG PS Eastern Cooperative Oncology Group Performance Status, NLR Neutrophil-to-Lymphocyte ratio, 95%CI 95% confidence interval
  2. *: P < 0.05 (Binomial logistic regression)
  3. ※: Not available due to multi-collinearity