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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: Niclosamide suppresses the expansion of follicular helper T cells and alleviates disease severity in two murine models of lupus via STAT3

Fig. 6

Niclosamide reduces the proportion of CD4+ T cells, TFH cells, GCs, and PCs in spleens of R848-induced mice. Spleen samples were collected from 12-week-old mice. a Data show proportion of CD4+ T cells (CD4+ CD8− gated on FVD− CD90.2+). b Bar graphs show mean ± SD. c Data show proportion of TFH cells (CXCR5+ PD-1+ gated on CD4+). d Bar graphs show mean ± SD. e Data show proportion of GC B cells (CD138− GL7+ gated on CD19+). f Bar graphs show mean ± SD. g Data show proportion of PCs (CD19− CD138+ gated on CD19−). h Bar graphs show mean ± SD. One-way ANOVA was performed. **P < 0.01

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