Fig. 2
Niclosamide modulates the proportion of CD90.2+ T cells, DNT cells, TFH cells and PCs in the spleen and PB of MRL/lpr mice. Spleen and PB samples were collected from 16-week-old mice. a comparison of the FVD− and CD90.2+ T-cell proportion. The gating strategies were: lymphocytes as FSC-A vs SSC-A, live cells as FVD-A vs CD90.2-A b Bar graphs show mean ± SD. c Altered proportion of DNT cells (CD4− CD8− gated on FVD− CD90.2+) by niclosamide. d Bar graphs show mean ± SD. e Data show proportion of TFH cells (CXCR5+ PD-1+ gated on CD4 +). f Bar graphs show mean ± SD. g Data show proportion of PCs (CD19− CD138+ gated on CD19−). h Bar graphs show mean ± SD. t-test was performed. *P < 0.05, **P < 0.01