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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Identification of susceptibility loci for cardiovascular disease in adults with hypertension, diabetes, and dyslipidemia

Fig. 2

Manhattan Plots Showing Association Results of the GWASs. Manhattan plots showing association results from the GWASs of CVD in the HTN(A–C), DM(D–F), and DL(G–I) groups within the City Cohort: a HTN-CAD (816 CAD cases and 15,488 controls), b HTN-IS (398 IS cases and 15,909 controls), c HTN-CCD (1,185 CCD cases and 15,117 controls), d DM-CAD (361 CAD cases and 5,161 controls), e DM-IS (153 IS cases and 5,161 controls), f DM-CCD (497 CCD cases and 4,815 controls), g DL-CAD (768 CAD cases and 19,999 controls), h DL-IS (295 IS cases and 20,474 controls), and i DL-CCD (1,039 CCD cases and 19,727 controls). Each tested SNP is visualized as a dot with a location on the genome shown on the x-axis and log10- transformed p values on the y-axis. Results for all chromosomes within the consensus threshold for genome-wide significance (5 × 10−8) are marked with a horizontal line in red and suggestive significance (1 × 10–5) in blue

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