Skip to main content

Table 3 Model fit among seven models including or not including NTRK3 methylation status

From: Genome-wide analysis identifies critical DNA methylations within NTRKs genes in colorectal cancer

Models N AIC LR P value
Model 1 219 597.73 6.91  
Model 2 219 600.69 5.95 0.005a
Model 3 219 592.41 16.23 0.002b
Model 4 219 516.49 39.06  
Model 5 219 513.91 43.64 0.032c
  1. N: patient counts in each model; AIC: Akaike information criterion value; LR: likelihood ratio
  2. Model 1 includes NTRK3 hypermethylation
  3. Model 2 includes TNM stage (I, II, III)
  4. Model 3 includes TNM stage (I, II, III), NTRK3 hypermethylation
  5. Model 4 includes age at diagnosis, sex (m/f), location(left colon, right colon, rectum), differentiation (well, moderate, poor), lymphovascular invasion, perineural invasion (n/y), T stage (T1, T2, T3, T4), N stage (N0, N1, N2), negative lymph node number, preoperation CEA, chemotherapy(n/y)
  6. Model 5 includes NTRK3 hypermethylation and all variables in Model 4
  7. aP values for the LR test in model 1 compared with model 2; bP values for the LR test in model 2 compared with model 3; cP values for the LR test in model 4 compared with model 5