Table 5 Baseline characteristics changes in 5-year follow-up survey of various rs1044250 genotypes in the Control group and the Mets group

Sex (male%)

47.7%

57.1%

49.0%

47.5%

39.7%

30.8%

45.9%

Age (years)

51.64 ± 9.30

51.07 ± 10.51

51.56 ± 9.45

51.42 ± 9.68

52.47 ± 10.20

54.00 ± 10.57

51.65 ± 9.79

ΔWeight (kg)

− 0.31 ± 1.64

− 0.52 ± 1.66

− 0.37 ± 1.64

− 2.11 ± 3.11

− 1.98 ± 2.78

− 1.90 ± 1.50

− 2.08 ± 3.03^c

ΔBMI (kg/m²)

0.09 ± 0.86

− 0.02 ± 0.65

0.07 ± 0.84

− 0.55 ± 1.08

− 0.51 ± 1.00

− 0.46 ± 0.63

− 0.54 ± 1.06^c

ΔWC (cm)

− 0.54 ± 3.02

− 0.98 ± 2.24

− 0.60 ± 2.92

− 4.37 ± 3.36

− 3.91 ± 3.08

− 4.27 ± 3.45

− 4.28 ± 3.31^c

ΔSBP (mmHg)

1.07 ± 6.79

0.17 ± 5.53

0.95 ± 6.62

− 7.16 ± 13.39

− 6.90 ± 11.75

− 4.13 ± 8.09

− 7.06 ± 13.04^c

ΔDBP (mmHg)

− 0.27 ± 2.53

0.38 ± 1.59

− 0.18 ± 2.43

− 5.46 ± 6.85

− 5.17 ± 6.69

− 4.97 ± 6.96

− 5.40 ± 6.82^c

ΔTG (mmol/L)

0.32 ± 0.50

0.23 ± 0.58

0.31 ± 0.51

− 0.84 ± 1.81

− 0.70 ± 1.43

− 1.02 ± 1.90

− 0.82 ± 1.75^c

ΔTC (mmol/L)

0.13 ± 1.08

− 0.08 ± 1.15

0.10 ± 1.09

− 0.33 ± 1.31

− 0.21 ± 1.33

− 0.75 ± 1.61

− 0.32 ± 1.32^c

ΔHDL-c (mmol/L)

− 0.24 ± 0.48

− 0.09 ± 0.36

− 0.22 ± 0.46

− 0.25 ± 0.66

− 0.32 ± 0.64

− 0.83 ± 1.12^{a, b}

− 0.27 ± 0.67

ΔFPG (mmol/L)

0.43 ± 1.42

0.59 ± 1.34

0.45 ± 1.41

− 0.12 ± 2.43

− 0.38 ± 2.53

− 0.10 ± 1.82

− 0.17 ± 2.44^c