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Table 5 Baseline characteristics changes in 5-year follow-up survey of various rs1044250 genotypes in the Control group and the Mets group

From: Cross-talk between ANGPTL4 gene SNP Rs1044250 and weight management is a risk factor of metabolic syndrome

  Control Mets
CC (n = 174) CT + TT (n = 28) Total (n = 202) CC (n = 667) CT (n = 151) TT (n = 13) Total (n = 202)
Sex (male%) 47.7% 57.1% 49.0% 47.5% 39.7% 30.8% 45.9%
Age (years) 51.64 ± 9.30 51.07 ± 10.51 51.56 ± 9.45 51.42 ± 9.68 52.47 ± 10.20 54.00 ± 10.57 51.65 ± 9.79
ΔWeight (kg) − 0.31 ± 1.64 − 0.52 ± 1.66 − 0.37 ± 1.64 − 2.11 ± 3.11 − 1.98 ± 2.78 − 1.90 ± 1.50 − 2.08 ± 3.03c
ΔBMI (kg/m2) 0.09 ± 0.86 − 0.02 ± 0.65 0.07 ± 0.84 − 0.55 ± 1.08 − 0.51 ± 1.00 − 0.46 ± 0.63 − 0.54 ± 1.06c
ΔWC (cm) − 0.54 ± 3.02 − 0.98 ± 2.24 − 0.60 ± 2.92 − 4.37 ± 3.36 − 3.91 ± 3.08 − 4.27 ± 3.45 − 4.28 ± 3.31c
ΔSBP (mmHg) 1.07 ± 6.79 0.17 ± 5.53 0.95 ± 6.62 − 7.16 ± 13.39 − 6.90 ± 11.75 − 4.13 ± 8.09 − 7.06 ± 13.04c
ΔDBP (mmHg) − 0.27 ± 2.53 0.38 ± 1.59 − 0.18 ± 2.43 − 5.46 ± 6.85 − 5.17 ± 6.69 − 4.97 ± 6.96 − 5.40 ± 6.82c
ΔTG (mmol/L) 0.32 ± 0.50 0.23 ± 0.58 0.31 ± 0.51 − 0.84 ± 1.81 − 0.70 ± 1.43 − 1.02 ± 1.90 − 0.82 ± 1.75c
ΔTC (mmol/L) 0.13 ± 1.08 − 0.08 ± 1.15 0.10 ± 1.09 − 0.33 ± 1.31 − 0.21 ± 1.33 − 0.75 ± 1.61 − 0.32 ± 1.32c
ΔHDL-c (mmol/L) − 0.24 ± 0.48 − 0.09 ± 0.36 − 0.22 ± 0.46 − 0.25 ± 0.66 − 0.32 ± 0.64 − 0.83 ± 1.12a, b − 0.27 ± 0.67
ΔFPG (mmol/L) 0.43 ± 1.42 0.59 ± 1.34 0.45 ± 1.41 − 0.12 ± 2.43 − 0.38 ± 2.53 − 0.10 ± 1.82 − 0.17 ± 2.44c
  1. Continuous variables are recorded by \(\stackrel{-}{x}\pm S\); Categorical variables are recorded in proportions
  2. Mets: metabolic syndrome; BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; TC: total cholesterol; HDL-c: high-density lipoprotein-cholesterol; FPG: fasting plasma glucose
  3. aStatistically significant compared with CC genotype in the Mets group
  4. bStatistically significant compared with CT genotype in the Mets group
  5. cStatistically significant compared with the Mets group; Δ, follow-up values minus baseline values