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Table 4 Logistic regression analysis of Mets and Mets components

From: Cross-talk between ANGPTL4 gene SNP Rs1044250 and weight management is a risk factor of metabolic syndrome

  Independent variables β p OR 95% CI
Lower Upper
Mets Sex (male vs female) − 0.812  < 0.001 0.444 0.313 0.630
Age (years) 0.019 0.009 1.019 1.005 1.034
Weight (kg) 0.081  < 0.001 1.085 1.055 1.115
BMI (kg/m2) 0.351  < 0.001 1.420 1.308 1.541
LDL-c (mmol/L) 1.210  < 0.001 3.355 2.699 4.171
rs1044250 0.629  < 0.001 1.875 1.363 2.580
Increased WC Sex (male vs female) − 2.367  < 0.001 0.094 0.059 0.149
Age (years) 0.033  < 0.001 1.034 1.015 1.053
Weight (kg) 0.104  < 0.001 1.110 1.073 1.148
BMI (kg/m2) 0.265  < 0.001 1.303 1.185 1.434
TG (mmol/L) 0.328  < 0.001 1.388 1.225 1.573
HDL-c (mmol/L) − 0.372 0.029 0.689 0.493 0.963
SBP (mmHg) 0.046  < 0.001 1.047 1.033 1.060
DBP (mmHg) 0.068  < 0.001 1.070 1.047 1.094
rs1044250 0.481 0.011 1.618 1.119 2.340
Elevated BP Age (years) 0.035  < 0.001 1.036 1.024 1.048
BMI (kg/m2) 0.327  < 0.001 1.387 1.338 1.438
FPG (mmol/L) 0.308  < 0.001 1.361 1.237 1.497
LDL-c (mmol/L) 0.535  < 0.001 1.708 1.439 2.028
rs1044250 0.280 0.048 1.323 1.002 1.747
Increased TG BMI (kg/m2) 0.095  < 0.001 1.099 1.051 1.150
WC (cm) 0.065  < 0.001 1.067 1.048 1.086
TC (mmol/L) 0.708  < 0.001 2.030 1.778 2.319
FPG (mmol/L) 0.146  < 0.001 1.158 1.079 1.242
DBP (mmHg) 0.049  < 0.001 1.050 1.038 1.062
rs1044250 0.046 0.752 1.047 0.786 1.395
Decreased HDL-c Sex (male vs female) 0.491  < 0.001 1.634 1.332 2.004
WC (cm) 0.028  < 0.001 1.028 1.016 1.040
DBP (mmHg) 0.022  < 0.001 1.022 1.012 1.032
rs1044250 − 0.078 0.532 0.925 0.723 1.182
Increased FPG WC (cm) 0.046  < 0.001 1.048 1.034 1.062
TC (mmol/L) 0.647  < 0.001 1.911 1.601 2.281
TG (mmol/L) 0.140 0.002 1.151 1.054 1.256
HDL-c (mmol/L) − 0.447 0.016 0.640 0.444 0.921
SBP (mmHg) 0.013 0.001 1.013 1.005 1.021
DBP (mmHg) 0.018 0.011 1.018 1.004 1.032
rs1044250 0.126 0.361 1.135 0.866 1.487
  1. rs1044250, (CC = 0, TC = 1, TT = 2); OR, odds ratio; 95% CI, 95% confidence interval
  2. Mets: metabolic syndrome; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; TG: triglyceride; TC: total cholesterol; HDL-c: high-density lipoprotein-cholesterol; LDL-c: low-density lipoprotein-cholesterol; WC: waist circumference; FPG: fasting plasma glucose