Fig. 1From: Cross-talk between ANGPTL4 gene SNP Rs1044250 and weight management is a risk factor of metabolic syndromeRoles of ANGPTL4. a Muscle-derived ANGPTL4 levels is increased during exercise or fasting; b, c ANGPTL4 involves in the process of neovascularization and lymphangiogenesis; d ANGPTL4 improves glucose tolerance through an intestinal microbiota dependent mechanism; e ANGPTL4 involves in the hypothalamic regulation of appetite, energy consumption and lipid deposition; f ANGPTL4 promotes the lipolysis of white adipose tissue by inhibiting lipoprotein lipase (LPL) activity, which mediate the decomposition of triglyceride (TG) to free fatty acid (FFA); in cold exposure, ANGPTL4 mediates the FFA transportation through white adipose tissue to brown adipose tissueBack to article page