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Table 2 List of phosphorylated substrates in cell lines treated with exogenous, purified DnaK

From: Exogenous bacterial DnaK increases protein kinases activity in human cancer cell lines

Phosphorylated substrate

Cell line

HCT116

PC3

SHSY5Y not differentiated

SHSY5Y differentiated

β-Catenin

   

x

CREB1

    

HSP27

S78/S82

 

S78, S82

S78, S82

HSP60

x

  

x

c-JUN

  

S63

S63

eNOS

  

S1177

 

p27

  

T198

T198

p53

 

S15

S15, S46, S392

S15, S46, S392

PLC-γ1

   

Y783

PRAS40

T246

   

STAT2

   

Y689

STAT3

  

Y705, S727

 

STAT5a

 

xY699

 

xY694

  1. Numbers represents phosphorylation sites
  2. S serine, T threonine, Y tyrosine, P protein phosphorylated, unknown site