Table 1 List of phosphorylated kinases in cell lines treated with exogenous, purified DnaK
From: Exogenous bacterial DnaK increases protein kinases activity in human cancer cell lines
Phosphorylated kinase | Cell line | Kinase family | Cancer association score | ||||
|---|---|---|---|---|---|---|---|
A549 | HCT116 | PC3 | SHSY5Y not differentiated | SHSY5Y differentiated | |||
EGF R Y1086 | Â | Â | Â | x | x | TK | 1 |
FAK Y397 | Â | x | Â | x | Â | TK | 1 |
Fgr Y412 | Â | Â | Â | Â | Â | TK | 1 |
Fyn Y420 | Â | Â | Â | x | Â | TK | 1 |
Hck Y411 | Â | x | Â | Â | Â | TK | 1 |
Lyn Y397 | Â | x | Â | Â | Â | TK | 1 |
Lck Y394 | Â | x | Â | Â | x | TK | 1 |
PDGF Rβ Y751 |  |  |  |  |  | TK | 1 |
PYK2 Y402 | Â | Â | Â | Â | Â | TK | 0.263 |
Src Y419 | Â | Â | Â | Â | Â | TK | 1 |
Yes Y426 | Â | Â | Â | Â | Â | TK | 1 |
Akt1/2/3 S473-T308 | Â | Â | x | x | x | AGC | 1 |
MSK1/2 S376/S360 | Â | Â | Â | x | x | AGC | N/A |
p70 S6 Kinase T421/S424 | Â | Â | x | Â | Â | AGC | 0.594 |
RSK1/2/3 S380/S386/S377 | Â | x | Â | x | Â | AGC | 0.490/0.516/0.872 |
AMPKα1 T183 |  |  |  |  | x | CAMK | 0.608 |
AMPKα2 T172 |  |  | x |  | x | CAMK | 0.983 |
Chk-2 T68 | Â | Â | Â | Â | Â | CAMK | 1 |
ERK1/2/3 T202/Y204, T185/Y187 | Â | Â | x | x | x | CMGC | 0.718/0.785 |
GSK3α/β S21/S9 |  |  |  |  | x | CMGC | 1 |
JNK1/2/3 T183/Y185, T221/Y223 | Â | Â | Â | Â | x | CMGC | 0.572/0.516/0.440 |
p38a T180/Y182 | x | Â | Â | Â | Â | CMGC | 0.291 |
WNK1 T60 | Â | Â | Â | x | x | STE | 0.283 |
TOR S2448 | Â | Â | Â | x | Â | Atypical | N/A |