Table 1 Correlations between ARHGAP9 expression and clinicopathological feathers in AML from TCGA cohort
From: The role of ARHGAP9: clinical implication and potential function in acute myeloid leukemia
| Patient characteristics | ARHGAP9 expression | ||
|---|---|---|---|
| Low (n = 76) | High (n = 75) | p | |
| Sex, male/female | 38/38 | 45/30 | 0.217 |
| Median age, years (range) | 53.5 (21–77) | 60 (21–88) | 0.091 |
| Median BM blasts, % (range) | 75 (30–100) | 69 (30–99) | 0.071 |
| Median WBC, × 109/L (range) | 13.35 (0.4–137.2) | 27.6 (0.6–223.8) | 0.194 |
| Median PB blasts, % (range) | 40 (0–97) | 39 (0–96) | 0.322 |
| FAB classifications | |||
| M0 | 6 | 9 | 0.399 |
| M1 | 12 | 24 | 0.019 |
| M2 | 14 | 23 | 0.067 |
| M3 | 14 | 0 | 0 |
| M4 | 16 | 5 | 0.011 |
| M5 | 10 | 1 | 0.005 |
| M6 | 1 | 0 | 1 |
| M7 | 1 | 0 | 1 |
| NA | 1 | 0 | 1 |
| Cytogenetics | |||
| Normal | 24 | 37 | 0.026 |
| t(8;21) | 3 | 4 | 0.719 |
| t(15;17) | 14 | 0 | < 0.001 |
| inv.(16) | 7 | 3 | 0.327 |
| + 8 | 5 | 3 | 1 |
| 11q23 | 7 | 1 | 0.063 |
| -7/del(7) | 2 | 4 | 0.442 |
| Complex | 5 | 13 | 0.041 |
| Others | 8 | 8 | 0.978 |
| No data | 1 | 2 | 1 |
| Risk level | |||
| Good | 24 | 7 | 0.001 |
| Intermediate | 34 | 45 | 0.060 |
| Poor | 17 | 21 | 0.453 |
| NA | 1 | 2 | 1 |