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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD

Fig. 3

Liver histopathology in NASH-STZ hamsters resembled NAFLD and insulin treatment improved hepatic steatosis. Top row: Macroscopic appearance of the livers from CTRL-, NASH-, NASH-STZ- and NASH-STZ-HI immediately after euthanization (left to right). ad Representative H&E stained sections of liver from CTRL-, NASH-, NASH-STZ- and NASH-STZ-HI hamsters (left to right). eh Representative Oil Red O stained sections of liver from CTRL-, NASH-, NASH-STZ- and NASH-STZ-HI hamsters (left to right). Insert in g: ×20 magnification of lipid accumulation in hepatocyte. Inserts in a-d: x20 magnifications of H&E-stained sections

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