TY - JOUR AU - Freedman, D. H. PY - 2019 DA - 2019// TI - Hunting for new drugs with AI JO - Nature VL - 576 UR - https://doi.org/10.1038/d41586-019-03846-0 DO - 10.1038/d41586-019-03846-0 ID - Freedman2019 ER - TY - STD TI - Drug development: the journey of a medicine from lab to shelf. . TOMORROW'S PHARMACIST 2015. https://www.pharmaceutical-journal.com/publications/tomorrows-pharmacist/drug-development-the-journey-of-a-medicine-from-lab-to-shelf/20068196.article?firstPass=false (view 10.20). UR - https://www.pharmaceutical-journal.com/publications/tomorrows-pharmacist/drug-development-the-journey-of-a-medicine-from-lab-to-shelf/20068196.article?firstPass=false ID - ref2 ER - TY - JOUR AU - Cunningham, S. PY - 2020 DA - 2020// TI - 3 tips for pharma startup success JO - Drug Discov Today VL - 25 UR - https://doi.org/10.1016/j.drudis.2020.06.024 DO - 10.1016/j.drudis.2020.06.024 ID - Cunningham2020 ER - TY - JOUR AU - Huggett, B. PY - 2020 DA - 2020// TI - In conversation with four startup CEOs JO - Nat Biotechnol VL - 38 UR - https://doi.org/10.1038/s41587-020-0498-z DO - 10.1038/s41587-020-0498-z ID - Huggett2020 ER - TY - JOUR AU - Ruffell, D. PY - 2019 DA - 2019// TI - The six steps to a successful start-up: an interview with Kai Simons JO - FEBS Lett VL - 593 UR - https://doi.org/10.1002/1873-3468.13354 DO - 10.1002/1873-3468.13354 ID - Ruffell2019 ER - TY - JOUR AU - Wlodarek, J. PY - 2014 DA - 2014// TI - Top tips for a successful practice start-up JO - J Mass Dent Soc VL - 63 ID - Wlodarek2014 ER - TY - CHAP AU - Strovel, J. AU - Sittampalam, S. AU - Coussens, N. P. ED - Markossian, S. ED - Sittampalam, G. S. ED - Grossman, A. ED - Brimacombe, K. ED - Arkin, M. ED - Auld, D. ED - Austin, C. P. ED - Baell, J. ED - Caaveiro, J. M. M. ED - Chung, T. D. Y. ED - Coussens, N. P. ED - Dahlin, J. L. ED - Devanaryan, V. ED - Foley, T. L. ED - Glicksman, M. ED - Hall, M. D. ED - Haas, J. V. ED - Hoare, S. R. J. ED - Inglese, J. ED - Iversen, P. W. ED - Kahl, S. D. ED - Kales, S. C. ED - Kirshner, S. ED - Lal-Nag, M. ED - Li, Z. ED - McGee, J. ED - McManus, O. ED - Riss, T. ED - Saradjian, P. ED - Trask, O. J. ED - Weidner, J. R. ED - Wildey, M. J. ED - Xia, M. ED - Xu, X. PY - 2004 DA - 2004// TI - Early drug discovery and development guidelines: for academic researchers, collaborators, and start-up companies BT - Assay Guidance Manual PB - Springer CY - Bethesda ID - Strovel2004 ER - TY - JOUR AU - Rubio, D. M. AU - Schoenbaum, E. E. AU - Lee, L. S. PY - 2010 DA - 2010// TI - Defining translational research: implications for training JO - Acad Med VL - 85 UR - https://doi.org/10.1097/ACM.0b013e3181ccd618 DO - 10.1097/ACM.0b013e3181ccd618 ID - Rubio2010 ER - TY - JOUR AU - Nakao, K. PY - 2019 DA - 2019// TI - Translational science: Newly emerging science in biology and medicine—lessons from translational research on the natriuretic peptide family and leptin JO - Proc Jpn Acad Ser B Phys Biol Sci VL - 95 UR - https://doi.org/10.2183/pjab.95.037 DO - 10.2183/pjab.95.037 ID - Nakao2019 ER - TY - JOUR AU - Stefely, J. A. AU - Theisen, E. AU - Hanewall, C. PY - 2019 DA - 2019// TI - A physician-scientist preceptorship in clinical and translational research enhances training and mentorship JO - BMC Med Educ VL - 19 UR - https://doi.org/10.1186/s12909-019-1523-0 DO - 10.1186/s12909-019-1523-0 ID - Stefely2019 ER - TY - JOUR AU - Kluijtmans, M. AU - Haan, E. AU - Akkerman, S. PY - 2017 DA - 2017// TI - Professional identity in clinician-scientists: brokers between care and science JO - Med Educ VL - 51 UR - https://doi.org/10.1111/medu.13241 DO - 10.1111/medu.13241 ID - Kluijtmans2017 ER - TY - JOUR AU - Jinawath, N. AU - Bunbanjerdsuk, S. AU - Chayanupatkul, M. PY - 2016 DA - 2016// TI - Bridging the gap between clinicians and systems biologists: from network biology to translational biomedical research JO - J Transl Med VL - 14 UR - https://doi.org/10.1186/s12967-016-1078-3 DO - 10.1186/s12967-016-1078-3 ID - Jinawath2016 ER - TY - JOUR AU - Shah, S. AU - Villemain, O. L. PY - 2020 DA - 2020// TI - Saving the endangered physician-scientists: reintroducing them to an environment of administrative support JO - J Investig Med VL - 68 UR - https://doi.org/10.1136/jim-2020-001544 DO - 10.1136/jim-2020-001544 ID - Shah2020 ER - TY - JOUR AU - Perumalswami, C. R. AU - Takenoshita, S. AU - Tanabe, A. PY - 2020 DA - 2020// TI - Workplace resources, mentorship, and burnout in early career physician-scientists: a cross sectional study in Japan JO - BMC Med Educ VL - 20 UR - https://doi.org/10.1186/s12909-020-02072-x DO - 10.1186/s12909-020-02072-x ID - Perumalswami2020 ER - TY - JOUR AU - Iness, A. N. PY - 2019 DA - 2019// TI - Waiting to "make it" versus "making it happen": empowering physician-scientists in training JO - J Clin Invest VL - 129 UR - https://doi.org/10.1172/JCI131669 DO - 10.1172/JCI131669 ID - Iness2019 ER - TY - JOUR AU - Strong, M. J. AU - Busing, N. AU - Goosney, D. L. PY - 2018 DA - 2018// TI - The rising challenge of training physician-scientists: recommendations from a canadian national consensus conference JO - Acad Med VL - 93 UR - https://doi.org/10.1097/ACM.0000000000001857 DO - 10.1097/ACM.0000000000001857 ID - Strong2018 ER - TY - JOUR AU - Patel, S. A. AU - Minn, A. J. PY - 2018 DA - 2018// TI - Combination cancer therapy with immune checkpoint blockade: mechanisms and strategies JO - Immunity VL - 48 UR - https://doi.org/10.1016/j.immuni.2018.03.007 DO - 10.1016/j.immuni.2018.03.007 ID - Patel2018 ER - TY - JOUR AU - Ilan, Y. PY - 2018 DA - 2018// TI - Analogy between non-alcoholic steatohepatitis (NASH) and hypertension: a stepwise patient-tailored approach for NASH treatment JO - Ann Gastroenterol VL - 31 ID - Ilan2018 ER - TY - JOUR AU - Ilan, Y. PY - 2020 DA - 2020// TI - Overcoming compensatory mechanisms toward chronic drug administration to ensure long-term, sustainable beneficial effects JO - Mol Ther Methods Clin Dev VL - 18 UR - https://doi.org/10.1016/j.omtm.2020.06.006 DO - 10.1016/j.omtm.2020.06.006 ID - Ilan2020 ER - TY - JOUR AU - Loscher, W. AU - Potschka, H. AU - Sisodiya, S. M. PY - 2020 DA - 2020// TI - Drug resistance in epilepsy: clinical impact, potential mechanisms, and new innovative treatment options JO - Pharmacol Rev VL - 72 UR - https://doi.org/10.1124/pr.120.019539 DO - 10.1124/pr.120.019539 ID - Loscher2020 ER - TY - JOUR AU - Reus, G. Z. AU - Moura, A. B. AU - Borba, L. A. PY - 2019 DA - 2019// TI - Strategies for treatment-resistant depression: lessons learned from animal models JO - Mol Neuropsychiatry VL - 5 UR - https://doi.org/10.1159/000500324 DO - 10.1159/000500324 ID - Reus2019 ER - TY - STD TI - Kolben Y, Weksler-Zangen S, Ilan Y. Adropin as a potential mediator of the metabolic system-autonomic nervous system-chronobiology axis: Implementing a personalized signature-based platform for chronotherapy. Obes Rev. 2020;7:27. ID - ref22 ER - TY - JOUR AU - Potruch, A. AU - Khoury, S. T. AU - Ilan, Y. PY - 2020 DA - 2020// TI - The role of chronobiology in drug-resistance epilepsy: the potential use of a variability and chronotherapy-based individualized platform for improving the response to anti-seizure drugs JO - Seizure VL - 80 UR - https://doi.org/10.1016/j.seizure.2020.06.032 DO - 10.1016/j.seizure.2020.06.032 ID - Potruch2020 ER - TY - JOUR AU - Forkosh, E. AU - Kenig, A. AU - Ilan, Y. PY - 2020 DA - 2020// TI - Introducing variability in targeting the microtubules: review of current mechanisms and future directions in colchicine therapy JO - Pharmacol Res Perspect VL - 8 UR - https://doi.org/10.1002/prp2.616 DO - 10.1002/prp2.616 ID - Forkosh2020 ER - TY - JOUR AU - Gelman, R. AU - Bayatra, A. AU - Kessler, A. PY - 2020 DA - 2020// TI - Targeting SARS-CoV-2 receptors as a means for reducing infectivity and improving antiviral and immune response: an algorithm-based method for overcoming resistance to antiviral agents JO - Emerg Microbes Infect VL - 9 UR - https://doi.org/10.1080/22221751.2020.1776161 DO - 10.1080/22221751.2020.1776161 ID - Gelman2020 ER - TY - JOUR AU - Ilan, Y. PY - 2020 DA - 2020// TI - Order through disorder: the characteristic variability of systems JO - Front Cell Dev Biol VL - 8 UR - https://doi.org/10.3389/fcell.2020.00186 DO - 10.3389/fcell.2020.00186 ID - Ilan2020 ER - TY - JOUR AU - Kenig, A. AU - Ilan, Y. PY - 2019 DA - 2019// TI - A personalized signature and chronotherapy-based platform for improving the efficacy of sepsis treatment JO - Front Physiol VL - 10 UR - https://doi.org/10.3389/fphys.2019.01542 DO - 10.3389/fphys.2019.01542 ID - Kenig2019 ER - TY - JOUR AU - Khoury, T. AU - Ilan, Y. PY - 2019 DA - 2019// TI - Introducing patterns of variability for overcoming compensatory adaptation of the immune system to immunomodulatory agents: a novel method for improving clinical response to anti-TNF therapies JO - Front Immunol VL - 10 UR - https://doi.org/10.3389/fimmu.2019.02726 DO - 10.3389/fimmu.2019.02726 ID - Khoury2019 ER - TY - JOUR AU - El-Haj, M. AU - Kanovitch, D. AU - Ilan, Y. PY - 2019 DA - 2019// TI - Personalized inherent randomness of the immune system is manifested by an individualized response to immune triggers and immunomodulatory therapies: a novel platform for designing personalized immunotherapies JO - Immunol Res VL - 67 UR - https://doi.org/10.1007/s12026-019-09101-y DO - 10.1007/s12026-019-09101-y ID - El-Haj2019 ER - TY - JOUR AU - Kessler, A. AU - Weksler-Zangen, S. AU - Ilan, Y. PY - 2020 DA - 2020// TI - Role of the immune system and the circadian rhythm in the pathogenesis of chronic pancreatitis: establishing a personalized signature for improving the effect of immunotherapies for chronic pancreatitis JO - Pancreas VL - 49 UR - https://doi.org/10.1097/MPA.0000000000001626 DO - 10.1097/MPA.0000000000001626 ID - Kessler2020 ER -