Fig. 6

Long-term L. edodes derived β-glucan supplementation alleviated the synaptic impairment in the hippocampus of mice fed HF diet. a Representative electron micrograph of synaptic ultrastructure in the hippocampus cornus ammonis (CA1), CA3 and dentate gyrus (DG) regions, b statistical analysis of the thickness of PSD, the width of synaptic cleft (c), and curvature of the synaptic interface in the hippocampus (d), e protein expression levels of BDNF and PSD-95 in the hippocampus. Data are presented as mean ± SEM. n = 3 per group. ^*P < 0.05, ^**P < 0.01, vs lab chow diet group (LC); ^#P < 0.05, ^##P < 0.01, vs high-fat diet group (HF). HFL, L. edodes β-glucan supplementation in HF diet group