Table 2 COVID-19 severity assessment (COSA) score parameters and evaluation
Parameter | Value | Score points |
|---|---|---|
Sex | Male | 1 |
CRP |  ≥ 25 mg/L | 3 |
Sodium |  ≥ 144 mmol/L | 2 |
Hemoglobin |  ≤ 100 g/L | 1 |
eGFR according to CKD-EPI |  ≤ 75 mL/min | 1 |
Glucose |  ≥ 8.6 mmol/L | 1 |
Leucocytes |  ≥ 10 G/L | 1 |
Score evaluation | |||
|---|---|---|---|
Total score per patient | Category | % patients (training, validation) | % severe outcome (training, validation) |
0–3 points: | Low risk for severe COVID-19 (< 5%) | 37.9, 38.4% | 0, 4.5% |
4–5 points: | Moderate risk for severe COVID-19 (< 50%) | 34.8, 32.5% | 24.6, 15.4% |
6–7 points: | High risk for severe COVID-19 (> 50%) | 12.1, 19.4% | 70.8, 46.1% |
8–10 points: | Very high risk for severe COVID-19 (> 90%) | 15.2, 9.6% | 96.7, 75.0% |