Table 1 General characteristics and laboratory parameters of the training cohort (n = 198) and validation cohort (n = 459)

65.0 (53.5, 79.5)

54.0 (36.0, 71.5)

 < 0.002^a

69.0 (61.0, 79.0)

62.0 (46.0, 75.0)

 < 0.002^a

11 (17.46%)

69 (51.11%)

 < 0.002^b

33 (31.43%)

150 (42.49%)

0.055^b

61 (96.83%)

84 (62.22%)

 < 0.002^b

102 (97.14%)

216 (61.19%)

 < 0.002^b

25 (39.68%)

0 (0.00%)

 < 0.002^b

33 (31.43%)

0 (0.00%)

 < 0.002^b

83.00 (70.40, 97.00)

75.65 (62.00, 87.00)

0.241^a

80.60 (70.00, 90.15)

77.20 (65.70, 87.00)

0.989^a

172.00 (165.00, 178.25)

170.00 (163.00, 177.00)

0.012^a

170.00 (165.00, 176.00)

170.00 (164.00, 176.00)

0.037^a

27.62 (24.80, 31.57)

25.82 (22.52, 28.95)

0.018^a

28.10 (24.95, 32.62)

26.23 (23.62, 29.59)

 < 0.002^a

176.00 (92.75, 279.75)

22.00 (6.00, 67.00)

 < 0.002^a

146.00 (72.75, 228.25)

35.00 (8.00, 89.00)

 < 0.002^a

142.00 (139.50, 146.00)

139.00 (136.00, 141.00)

 < 0.002^a

142.00 (139.00, 145.00)

139.00 (137.00, 141.00)

 < 0.002^a

96.00 (78.25, 115.00)

132.00 (119.00, 141.00)

 < 0.002^a

110.00 (86.00, 122.00)

128.00 (116.00, 141.00)

 < 0.002^a

53.00 (25.00, 85.50)

87.00 (72.00, 104.00)

 < 0.002^a

62.50 (32.50, 81.00)

82.00 (59.00, 98.00)

 < 0.002^a

10.10 (8.00, 12.75)

6.10 (5.48, 7.62)

 < 0.002^a

10.70 (8.30, 13.50)

6.42 (5.60, 8.20)

 < 0.002^a

10.60 (7.83, 17.55)

5.92 (4.70, 7.77)

 < 0.002^a

12.30 (8.95, 16.00)

6.73 (4.97, 8.78)

 < 0.002^a

11 (17.46%)

16 (11.85%)

0.400^b

–

–

–

5 (7.94%)

11 (8.15%)

1^b

–

–

–

47 (74.60%)

56 (41.48%)

 < 0.002^b

–

–

–

35 (55.56%)

43 (31.85%)

0.003^b

–

–

–

13 (20.63%)

6 (4.44%)

 < 0.002^b

–

–

–

16 (25.40%)

14 (10.37%)

0.011^b

–

–

–

8 (12.70%)

11 (8.15%)

0.451^b

–

–

–

16 (25.40%)

24 (17.78%)

0.292^b

–

–

–

18 (28.57%)

35 (25.93%)

0.826^b

–

–

–

4 (6.35%)

15 (11.11%)

0.423^b

–

–

–

6 (9.52%)

5 (3.70%)

0.183^b

–

–

–

10 (15.87%)

19 (14.07%)

0.906^b

–

–

–

22 (34.92%)

20 (14.81%)

0.002^b

–

–

–

6 (9.52%)

16 (11.85%)

0.808^b

–

–

–