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Table 2 AFP, free β-hCG and DD (MoM) in the different groups at the screening

From: Second trimester maternal serum D-dimer combined with alpha-fetoprotein and free β-subunit of human chorionic gonadotropin predict hypertensive disorders of pregnancy: a systematic review and retrospective case–control study

Groups

n

DD MoM

AFP MoM

Free β-hCG MoM

Control

136

0.89 (0.50–1.42)

0.96 (0.58–1.68)

1.02 (0.36–3.24)

GH

126

1.02 (0.77–1.23)

0.98 (0.58–1.65)

0.93 (0.40–2.71)

PE

53

1.16 (0.69–1.47)

0.99 (0.47–1.62)

0.97 (0.24–2.80)

SPE

41

1.34 (1.06–1.64)

1.09 (0.39–2.23)

1.07 (0.43–3.52)

P

 

 < 0.001*

0.009**

0.309

  1. DD D-dimer, AFP alpha-fetoprotein, free β-hCG free β subunit of human chorionic gonadotropin, GH gestational hypertension, PE preeclampsia, SPE severe preeclampsia, MoM multiple of the median.*P < 0.001; **P < 0.05