Second trimester maternal serum D-dimer combined with alpha-fetoprotein and free β-subunit of human chorionic gonadotropin predict hypertensive disorders of pregnancy: a systematic review and retrospective case–control study

Table 1 Comparison of demographic data in the second trimester between the different groups

Groups	n	Maternal age (years)	Gestational age at testing (days)	Maternal weight (kg)
Control	136	28.26 ± 2.67	118.00 ± 4.00	53.64 ± 5.41
GH	126	28.84 ± 3.35	117.00 ± 5.00	63.06 ± 11.35
PE	53	28.86 ± 2.98	118.00 ± 6.00	59.68 ± 11.26
SPE	41	28.83 ± 3.05	118.00 ± 4.00	57.02 ± 8.32
P		0.368	0.225	< 0.001*

GH gestational hypertension, PE preeclampsia, SPE severe preeclampsia.*P < 0.001

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