Fig.9
From: Role of SIK1 in the transition of acute kidney injury into chronic kidney disease
Schematic model of the role of SIK1.AA stimulation down-regulated the expression of SIK1, leading to up-regulation of p-β-catenin (Y654) and nuclear accumulation of β-catenin, thus promoting the transcription of target genes by activating the WNT/β-catenin signaling pathway