Table 2 Examples of possible uses for HT management

Diabetes [33, 34]

Being overweight or obese, physical inactivity, high blood pressure, high cholesterol, tobacco smoking, unhealthy eating, heavy alcohol consumption

Cardiovascular disease [35, 36]

Being overweight or obese, physical inactivity, unhealthy eating, alcohol consumption, smoking, high blood pressure, diabetes, sodium intake

Breast cancer [37, 38]

Long-term use of combination hormone replacement therapy (oestrogen–progestin), obesity, alcohol consumption, late pregnancy or never being pregnant, night-shift work, physical inactivity

Lung cancer [39, 40]

Smoking (cigarette, cigar and pipe), second-hand smoking, beta carotene supplements in heavy smokers, alcohol consumption, exposure to chemicals, air pollution

TKA reoperation [17]

BMI, smoking, low activity, no sports, no long-distance walking

Autoimmune diseases [47]

Being obese, smoking, unhealthy eating, physical inactivity, exposure to certain infections, certain medications, exposure to toxic agents