1: Pain tolerant & good cognitions (n = 40) | 2: Restored HPA dynamics (n = 15) | 3: Orthostatic intolerance (n = 20) | 4: Low-grade inflammation (n = 4) | 5: Pain intolerant & poor cognitions (n = 33) | 6: High vagal activity (n = 3) | |
---|---|---|---|---|---|---|
Plasma cortisol, nmol/L-mean (SD) | 329 (118) | 314 (132) | 366 (132) | 407 (136) | 443 (154) | 462 (169) |
Urine cortisol:creatinine ratio, nmol/mmol-median (IQR) | 3.2 (2.2, 4.4) | 14.5 (7.0, 18.4) | 3.2 (2.5, 4.9) | 3.9 (2.8, 6.2) | 3.2 (1.8, 4.4) | 3.7 (n.a) |
Interferon gamma, pg/mL-median (IQR) | 84 (57, 119) | 102 (63, 199) | 125 (92, 250) | 174 (79, 223) | 65 (45, 116) | 167 (n.a) |
IP-10, pg/mL-median (IQR) | 345 (261, 479) | 419 (225, 467) | 314 (323, 410) | 2735 (2359, 3803) | 313 (174, 502) | 557 (n.a.) |
HF-HRV supine, ms2-median (IQR) | 1264 (422, 3262) | 1743 (147, 2630) | 869 (526, 2209) | 101 (52, 126) | 588 (198, 868) | 11052 (n.a.) |
Δ HR orthostatic response, beats/min-mean (SD) | 3.5 (3.2) | 2.5 (4.2) | 9.9 (4.1) | 3.9 (2.6) | 4.7 (3.7) | 7.8 (6.3) |
Δ SI orthostatic response, mL/m2-mean (SD) | − 4.3 (2.9) | − 3.0 (5.6) | − 11.4 (4.1) | − 2.8 (5.4) | − 4.3 (3.3) | − 9.4 (5.0) |
Pressure pain threshold, N/cm2-mean (SD) | 20.1 (7.6) | 16.5 (6.9) | 15.2 (5.2) | 13.2 (5.7) | 9.8 (3.9) | 17.1 (7.1) |
Digit span forward, total score-mean (SD) | 9.3 (2.1) | 8.7 (1.5) | 8.0 (2.1) | 8.5 (2.4) | 7.2 (1.2) | 8.0 (1.0) |
Color-Word interference test condition 2, sec-mean (SD) | 25.7 (4.2) | 22.9 (4.5) | 25.9 (4.4) | 25.3 (4.3) | 30.2 (9.2) | 23.7 (4.2) |