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Table 2 Response to immunotherapy based on anticoagulation status

From: Treatment with therapeutic anticoagulation is not associated with immunotherapy response in advanced cancer patients

Outcome Not on anticoagulation (n = 828) On anticoagulation (n = 120) p-value
Best overall response—no. (%)    0.80
Complete response (CR) 129 (15.6) 14 (11.7)  
Partial response (PR) 140 (16.9) 23 (19.2)  
Stable disease (SD) 144 (17.4) 22 (18.3)  
Progressive disease (PD) 395 (47.7) 60 (50.0)  
Could not be evaluated 10 (1.2) 1 (0.8)  
Objective response ratea    0.60
No. (%) 279 (33.6) 37 (30.8)  
95% CIb 30.4–37.0 22.7–40.0  
Disease control ratec    0.77
No. (%) 423 (51.1) 59 (49.2)  
95% CIb 47.6–54.5 40.0–58.4  
  1. aObjective response rate was defined as the percentage of patients who had CR or PR
  2. bThe 95% confidence intervals were calculated using the Clopper-Pearson method
  3. cDisease control rate was defined as the percentage of patients who had CR, PR or SD