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Table 2 Response to immunotherapy based on anticoagulation status

From: Treatment with therapeutic anticoagulation is not associated with immunotherapy response in advanced cancer patients

Outcome

Not on anticoagulation (n = 828)

On anticoagulation (n = 120)

p-value

Best overall response—no. (%)

  

0.80

Complete response (CR)

129 (15.6)

14 (11.7)

 

Partial response (PR)

140 (16.9)

23 (19.2)

 

Stable disease (SD)

144 (17.4)

22 (18.3)

 

Progressive disease (PD)

395 (47.7)

60 (50.0)

 

Could not be evaluated

10 (1.2)

1 (0.8)

 

Objective response ratea

  

0.60

No. (%)

279 (33.6)

37 (30.8)

 

95% CIb

30.4–37.0

22.7–40.0

 

Disease control ratec

  

0.77

No. (%)

423 (51.1)

59 (49.2)

 

95% CIb

47.6–54.5

40.0–58.4

 
  1. aObjective response rate was defined as the percentage of patients who had CR or PR
  2. bThe 95% confidence intervals were calculated using the Clopper-Pearson method
  3. cDisease control rate was defined as the percentage of patients who had CR, PR or SD