Fig. 6

KPNA2 contributes to the xenograft tumor growth of BCa in vivo by mediating the PRDM1/c-FOS pathway. a The curve displaying tumor volume at various time points. b The representative images of resected tumors and curve displaying tumor weight at various time points. c The expression of KPNA2, PRDM1 and c-FOS in transplanted tumor tissues determined by RT-qPCR. d The expression of KPNA2, PRDM1 and c-FOS in transplanted tumor tissues determined by Western blot analysis. e The tumor cell proliferation detected by EdU assay (×400). f The tumor cell apoptosis detected by TUNEL assay (×200). n = 12. * p < 0.05 vs. nude mice bearing T24 cells treated with oe-NC. ^#p < 0.05 vs. nude mice bearing T24 cells treated with oe-KPNA2