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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway

Fig. 5

The interaction between PRDM1 and c-FOS facilitates the malignant behaviors of BCa cells. a The targeting relationship between PRDM1 and c-FOS verified by hTFtarget. b The expression of PRDM1 determined by RT-qPCR. c The expression of PRDM1 determined by Western blot analysis. d The expression of c-FOS determined by RT-qPCR. e The expression of c-FOS determined by Western blot analysis. f The proliferation of BCa cells detected by CCK-8 assay. g The apoptosis of BCa cells detected by TUNEL staining (×200). h The number of migratory and invasive BCa cells detected by Transwell assay (×200). i migration of BCa cells detected by scratch test (×200). *p < 0.05 vs. T24 cells treated with oe-NC. #p < 0.05 vs. T24 cells treated with sh-NC. &p < 0.05 vs. T24 cells treated with oe-PRDM1

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