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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: KPNA2 interaction with CBX8 contributes to the development and progression of bladder cancer by mediating the PRDM1/c-FOS pathway

Fig. 3

CBX8 is required for the mediatory function of KPNA2 in BCa cell proliferation, migration and invasion. a The expression of CBX8 determined by RT-qPCR. *p < 0.05 vs. T24 cells treated with oe-KPNA2 + sh-NC. b, c The proliferation of BCa cells detected by CCK-8 assay. d The number of migratory and invasive BCa cells detected by Transwell assay (×200). e Migration of BCa cells detected by scratch test (×200). f The number of migratory and invasive BCa cells detected by Transwell assay (×200). g Migration of BCa cells detected by scratch test (×200). *p < 0.05 vs. T24 cells treated with oe-NC (panels b and d) or oe-NC + sh-NC (panels c and e). #p < 0.05 vs. T24 cells treated with sh-NC (panels b and d) or oe-KPNA2 + sh-NC (panels c and e)

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