Fig. 2

LINC01116 promotes CRC cell proliferation and angiogenesis. qRT-PCR was employed to measure LINC01116 expression in CRC cell lines (a). After pcDNA3.1-LINC01116 or sh-LINC01116 was transfected into SW480 and HCT116 cells, the mRNA of LINC01116 was measured by qRT-PCR (b). CCK-8 assay was used to determine cell viability (c), and colony formation assay to determine cell proliferation (d). Migration and angiogenesis were monitored by cell scratch (e) and tube formation assays (f), respectively. *P < 0.05, **P < 0.01; CRC colorectal cancer