Fig. 5

Abnormal expressions of lncRNAs were positively correlated with abnormal copy numbers. a Distribution of lncRNA copy number amplification and deletion in genome. b The correlation distribution between lncRNA expressions and CNVs, light blue represents the distribution under random conditions, orange represents the distribution under actual conditions, t-test was used to examine the difference. c The lncRNAs located in the focal CNA peaks are cervical cancer-related. False-discovery rates and scores from GISTIC 2.0 for alterations (x-axis) are plotted against genome positions (y-axis); dotted lines indicate the centromeres. The deletions (right, blue) and amplifications (left, red) of lncRNAs genes are also shown. The green line represents 0.05 (FDR) as cut-off point that determines significance. d The expressions of lncRNAs in the samples with copy amplification are significantly higher than that in the samples with normal copies