Fig. 1

Flow chart of inclusion. All 27 participants (8 DM1 patients, 7 HME patients, and 12 healthy controls) were allocated to and received the allocated intervention of LSD, HSD, and acute hypertonic saline infusion. *for the acute hypertonic saline infusion experiment, 11 healthy controls were analyzed, since blood sampling within the first 10 min after infusion proved to be problematic in one healthy control. DM1, type 1 diabetes. HME, hereditary multiple exostoses. LSD, low salt diet. HSD, high salt diet