Fig. 1

Overall analysis workflow and LASSO model profile plots for the potential prognostic indicators of HCC. a. Schematic flowchart of the workflow performed to build and validate the HCC prognostic model. b. LASSO coefficient profile plots of the 245 prognostic genes showing that the variations in the size of the coefficients of parameters shrink with an increasing value of the k penalty. c. Penalty plot for the LASSO model for the 245 prognostic genes with error bars denoting the standard errors. LASSO least absolute shrinkage and selection operator, HCC hepatocellular carcinoma, OS overall survival