Fig. 1From: The roles of osteocytes in alveolar bone destruction in periodontitisOsteocytes initiate bone remodeling through the regulation of osteoclasts and osteoblasts. (Top) Osteocytes express RANKL to promote, and OPG to inhibit, osteoclast generation and bone resorption. (Bottom) Osteocytes also secrete sclerostin and DKK1 to inhibit osteoblast formation and activityBack to article page