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Table 2 Cox-regression analysis of the correlation between IL-33 expression and prognostic parameters in HCC patients

From: Exogenous interleukin-33 promotes hepatocellular carcinoma growth by remodelling the tumour microenvironment

Parameter

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Age (year)

 (≥ 60 vs. < 60)

0.873 (0.452–1.684)

0.685

1.681 (0.797–3.543)

0.172

Number of tumours

 (Multiplies vs. Single)

1.579 (0.937–2.659)

0.086

1.863 (1.053–3.297)

0.033

Sex

 (Female vs. male)

0.341 (0.135–0.861)

0.023

0.351 (0.131–0.939)

0.037

Tumour size (cm)

 (> 5 vs. ≤ 5)

1.576 (0.862–2.883)

0.14

1.333 (0.680–2.616)

0.403

Capsule integrity

 (Yes vs. no)

0.513 (0.300–0.879)

0.015

0.637 (0.358–1.131)

0.124

Venous invasion

 (Yes vs. no)

2.54 (1.217–5.302)

0.013

2.596 (1.140–5.910)

0.023

IL-33 expression

 (High vs. low)

1.890 (1.111–3.216)

0.019

1.906 (1.099–3.305)

0.022

  1. Italic font indicates significant differences (P < 0.05)
  2. HR hazard ratio, CI confidence interval