Fig. 4

Combined cell-therapy with MDSCs and Treg decreases inflammatory cytokine expression. Immunohistochemical staining was performed to measure the expression of interleukin (IL)-17, IL-6, tumor necrosis factor (TNF)-α and Foxp3 in skin, liver, lung, intestine tissue from each groups at 28 days after BMT. (scale bar, 100 μM)