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Table 3 The complications and outcomes of COVID-19 in middle-aged (40–59 years) patients without comorbidities

From: Risk factors for severe COVID-19 in middle-aged patients without comorbidities: a multicentre retrospective study

Characteristics

All patients N = 119

Non-severe N = 101

Severe N = 18

p Valuea

ARDS

26 (21.8)

8 (7.9)

18 (100.0)

 < 0.001

Sepsis shock

5 (4.2)

0 (0)

5 (27.8)

0.003

Acute liver injury

16 (13.4)

8 (7.9)

8 (44.4)

 < 0.001

Acute kidney injury

3 (2.5)

1 (0.9)

2 (11.1)

0.059

Acute cardiac injury

4 (3.4)

0 (0)

4 (22.2)

 < 0.001

Time from symptom onset to ARDS (IQR),d

9 (7,12)

10 (8,11)

8 (7,12)

0.368

Time from symptom onset to sepsis shock, median (IQR),d

12 (9,20)

–

12 (9,20)

NS

Time from symptom onset to acute liver injury, median (IQR),d

12 (9,14)

11 (8,14)

13 (11,14)

0.397

Time from symptom onset to acute kidney injury, median (IQR),d

11 (10,16)

8 (–)

16 (14,19)

0.221

Time from symptom onset to acute cardiac injury, median (IQR),d

15 (13,17)

–

15 (13,17)

NS

Time from symptom onset to discharge or death, median (IQR),d

22 (19,26)

25 (22,30)

21 (19,26)

0.171

ICU admission

11 (9.24)

–

11 (61.1)

NS

Mechanical ventilation

18 (15.1)

–

18 (100)

NS

Vasopressor therapy

5 (4.2)

–

5 (27.8)

NS

CRRT

2 (1.68)

–

2 (11.1)

NS

ECMO

0(0)

–

0 (0)

NS

Death

5 (4.2)

0 (0)

5 (27.8)

0.003

  1. Values are numbers (percentages) unless stated otherwise
  2. COVID-19 coronavirus disease 2019, ARDS acute respiratory distress syndrome, IQR inter quartile range, ICU intensive care unit, CRRT continuous renal replacement therapy, ECMO extracorporeal membrane oxygenation
  3. a p values indicate differences between severe and non-severe. p < 0.05 was considered statistically significant