Table 2 The laboratory findings of COVID-19 in middle-aged (40–59 years) patients without comorbidities
Characteristics | All patients N = 119 | Non-severe N = 101 | Severe N = 18 | p valuea |
|---|---|---|---|---|
White blood cell count (3.5–9.5 × 109/L) | 7.76 (6.15,10.0) | 7.60 (6.11,9.03) | 9.00 (6.73,11.3) | 0.004 |
  < 4 (n,%) | 7 (5.9) | 7 (6.9) | 0 (0) | 0.543 |
 4–10 (n,%) | 93 (78.2) | 81 (80.2) | 12 (66.7) | 0.201 |
  > 10 (n,%) | 19 (16.0) | 13 (12.9) | 6 (33.3) | 0.029 |
Neutrophil count (1.8–6.3 × 109/L) | 5.73 (4.66,7.11) | 5.57 (4.47,6.91) | 7.61 (6.08,9.34) | 0.001 |
 > 6.3 (n,%) | 49 (41.2) | 37 (36.6) | 12 (66.7) | 0.017 |
Lymphocyte count (1.1–3.2 × 109/L) | 1.05 (0.73,1.57) | 1.17 (0.89,1.62) | 0.53 (0.44,0.77) |  < 0.001 |
 < 0.8 (n,%) | 36 (30.3) | 22 (21.8) | 14 (77.8) |  < 0.001 |
NLR | 4.97 (3.18,9.26) | 4.34 (3.06,7.11) | 14.9 (10.1,18.7) |  < 0.001 |
Haemoglobin (316-354Â g/L) | 128 (119,136) | 128 (119,136) | 130 (122,134) | 0.856 |
Platelet count (125–350 × 109/L) | 245 (191,302) | 245 (192,312) | 247 (167,273) | 0.313 |
 < 100 (n,%) | 3 (2.5) | 1 (1.0) | 2 (11.1) | 0.059 |
D-dimer (0–1.5 μg/ml) | 0.70 (0.34,1.23) | 0.62 (0.32,0.96) | 1.58 (1.09,3.78) |  < 0.001 |
 > 1 (n,%) | 36 (31.3) | 22 (22.4) | 14 (82.4) |  < 0.001 |
ALT (9-50U/L) | 31 (21,65) | 29 (19,59) | 55 (31,119) | 0.021 |
Prealbumin (200–430 mg/L) | 155 (104,219) | 161 (106,225) | 129 (99,165) | 0.162 |
Albumin (40–55 g/L) | 31.7 (29.8,35.8) | 32.4 (30.0,36.1) | 30.5 (27.8,31.7) | 0.014 |
Bilirubin (0-26μmmol/L) | 9.70 (6.70,14.3) | 9.80 (6.85,13.7) | 9.60 (6.48,17.2) | 0.986 |
Troponin (0–28 pg/mL) | 2.5 (0.9,4.3) | 2.4 (0.8,4.2) | 2.9 (1.3,5.5) | 0.572 |
Total cholesterol (3.3–5.2mmoL/L) | 3.83 (3.28,4.34) | 3.81 (3.28,4.36) | 3.95 (3.34,4.29) | 0.978 |
Triglyceride (0.51–1.70mmoL/L) | 1.42 (1.13,1.92) | 1.35 (1.11,1.89) | 1.48 (1.23,1.94) | 0.487 |
Low density lipoprotein (2.1–3.37mmoL/L) | 2.27 (1.83,2.78) | 2.27 (1.83,2.78) | 2.29 (1.81,2.72) | 0.830 |
High density lipoprotein (1.04–1.55 mmoL/L) | 0.92 (0.79,1.12) | 0.95 (0.79,1.14) | 0.89 (0.79,0.99) | 0.477 |
Serum creatinine (44–97 μmol/L) | 68.7 (55.9,77.8) | 69.4 (56.4,78.7) | 66.0 (53.7,69.6) | 0.159 |
Creatine kinase (0–190U/L) | 72.5 (43.0,123) | 67.0 (44.0,124) | 96.0 (39.5,121) | 0.618 |
CK-MB (0–25U/L) | 12.0 (10.0,16.0) | 12.0 (9.0,15.0) | 16.0 (10.8,18.0) | 0.069 |
HS-CRP (0–5 mg/L) | 27.7 (6.65,79.9) | 21.2 (6.10,79.2) | 45.2 (26.7,74.2) | 0.108 |
LDH (120–250 U/L) | 307 (225,363) | 290 (214,352) | 351 (299,454) | 0.007 |
IL-6 (0–7 pg/ml) | 8.33 (5.85,11.6) | 8.38 (5.87,11.6) | 7.62 (5.85,12.7) | 0.669 |
Procalcitonin (0–0.05 ng/ml) | 0.05 (0.05,0.05) | 0.05 (0.05,0.05) | 0.08 (0.05,0.10) | 0.002 |
SOFA score, median (IQR) | 1 (0,2) | 1 (0,2) | 2 (1,3) | 0.002 |
Unilateral pneumoniab (n, %) | 9 (7.6) | 9 (8.9) | 0 (0) | 0.352 |
Bilateral pneumoniac (n,%) | 110 (92.4) | 92 (91.1) | 18 (100) | 0.188 |