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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: Extracellular vesicle-encapsulated microRNA-424 exerts inhibitory function in ovarian cancer by targeting MYB

Fig. 7

The molecular mechanism of MSC-derived EVs carrying miR-424 in affecting ovarian cancer. miR-424 is delivered from MSCs to ovarian cancer cells via EVs. miR-424 targets and inhibits MYB expression. MSC-derived EVs carrying miR-424 repress the expression of VEGF, thus inhibiting the proliferation, migration and tube formation of HUVECs and further suppressing the tumorigenesis and angiogenesis of ovarian cancer

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Journal of Translational Medicine

ISSN: 1479-5876

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