Skip to main content
Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Extracellular vesicle-encapsulated microRNA-424 exerts inhibitory function in ovarian cancer by targeting MYB

Fig. 3

The proliferation, migration, and invasion of ovarian cancer cells are repressed by miR-424 via inhibition of MYB. The cells used for the following detections were treated with sh-NC, sh-MYB, miR-424 mimic or inhibitor as well as their NCs, and both miR-424 inhibitor and sh-MYB. a The expression of miR-424 and MYB in SKOV-3 cells after different treatments detected by RT-qPCR. b The protein expression of MYB in cells after different treatments examined by Western blot analysis. c The proliferation of SKOV-3 cells after different treatments determined by EdU assay. d The migration of SKOV-3 cells after different treatments detected by Transwell assay. e The invasion of SKOV-3 cells after different treatments examined by Transwell assay. f The protein expression of VEGF and VEGFR in cells after different treatments detected by Western blot analysis, with protein bands assessed; *p < 0.05 compared with cells treated with mimic-NC, #p < 0.05 compared with cells treated with inhibitor-NC; &p < 0.05 compared with cells treated with inhibitor NC. The data above were measurement data and were presented as sample mean ± standard deviation. Data among multiple groups were compared by one-way ANOVA, with Tukey’s post hoc test conducted. Data in each group at different time points were compared by repeated-measures one-way ANOVA. The cell experiment was repeated 3 times independently

Back to article page