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Table 3 BAL parameters

From: Cellular analysis of bronchoalveolar lavage fluid to narrow differential diagnosis of checkpoint inhibitor-related pneumonitis in metastatic melanoma

 

Patient 1

Patient 2

Patient 3

Patient 4

Patient 5

Normal range

Total cells (x 105/ml)

1,8

1,8

2,5

1,5

1,3

 

Macrophages

78%

80%

77%

72%

66%

75–85%

Neutrophils

0

0

5%

3%

2%

1–2%

Lymphocytes

22%

20%

26%

24%

30%

8–12%

Eosinophils

0

0

2%

1%

2%

0–0,5%

T CD3+

99%

95.8%

96%

95%

93%

70–90%

T CD4+

35%

17.2%

41%

38%

39%

35–45%

T CD8+

60.3%

77%

52%

47%

50%

30–40%

Natural killer CD3-CD16 + CD56+

0,70%

2,60%

3%

2%

3%

1–7%

B CD19+

0

0,50%

1%

1%

1%

0–7%

CD4/CD8 RATIO

0.6

0,2

0,7

0,8

0,7

0,8–2

CD3 + HLA-DR+

25.8%

36%

31%

24%

13%

 
  1. Flow cytometer of BAL in 5 melanoma patients with CIP