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Table 1 Characteristic of CRC patients with or without KRAS mutation

From: Immune landscape and prognostic immune-related genes in KRAS-mutant colorectal cancer patients

Characteristics CRC patients P-value
  KRAS-mutated (n=101) KRAS wild-type (n=234)  
Age 0.61
 [Median (IQR)] (year) 61 (49,68) 59.5 (51.25,67.75)  
Sex 0.85
 Male 62 (30.5) 141 (69.5)  
 Female 39 (29.5) 93 (70.5)  
Primary site 0.19
 Rectum 49 (33.8) 96 (66.2)  
 Left colon 22 (23.2) 73 (76.8)  
 Transverse colon 11 (40.7) 16 (59.3)  
 Right colon 19 (27.9) 49 (72.1)  
Pathological T classification 0.36
 T1-2  15 (36.6) 26 (63.4)  
 T3-4 86 (29.7) 204 (70.3)  
Pathological N classification 0.95
 N0 53 (30.5) 121 (69.5)  
 N1-2 44 (30.8) 99 (69.2)  
M classification 0.02*
 M0 83 (43.5) 108 (56.5)  
 M1 18 (27.3) 48 (72.7)  
Pathological stage 0.85
 I-II 47 (30.5) 107 (69.5)  
 III-IV 52 (31.5) 113 (68.5)  
Leukocyte (109/L) 6.70±2.16 6.85±2.60 0.614
Blood platelet (109/L) 283.94±99.25 292.55±108.71 0.495
Neutrophil (109/L) 3.82±2.24 4.36±3.53 0.157
Lymphocyte (109/L) 1.63±0.61 1.79±1.37 0.260
Albumin (g/L) 18.73±10.46 22.76±28.45 0.167
Total T lymphocyte (%) 65.77±9.76 65.58±1034 0.877
Helper T lymphocyte (%) 40.00±7.34 39.13±8.68 0.374
Suppressor t lymphocyte (%) 20.38±.82 20.67±7.27 0.739
Natural killer cell (%) 14.17±8.01 14.04±7.31 0.888
B-lymphocyte (%) 12.48±5.71 11.96±7.25 0.518
Immunoglobulin G (g/L) 11.86±3.12 11.54±2.98 0.369
Immunoglobulin M (g/L) 0.91±0.40 1.08±0.94 0.024*
Immunoglobulin A (g/L) 2.51±1.18 2.44±0.98 0.617
Complement C3 (g/L) 0.95±0.20 0.99±0.24 0.134
Complement C4 (g/L) 0.25±0.09 0.25±0.10 0.909
CRP (mg/L) 7.07±9.20 10.61±18.43 0.020*
hs-CRP (mg/L) 1.60±2.19 2.43±4.33 0.020*
  1. *P<0.05 CRP C-reactive protein, hs-CRP high-sensitivity C-reactive protein