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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: Immune landscape and prognostic immune-related genes in KRAS-mutant colorectal cancer patients

Fig. 1

Somatic mutation landscape of colorectal cancer (CRC) patients based on KRAS status. a Somatic mutation landscape of CRC patients with (left panel) or without (right panel) KRAS mutation. Seven common mutation types were counted. b Genes with significantly different mutation frequencies between the KRAS mutant and KRAS wild-type group. c Significantly different pathways between KRAS mutant and KRAS wild-type groups. Pathways significantly down regulated in KRAS-mutant CRC patients (left) and significantly up regulated in KRAS-mutant CRC patients (right). d The expression of key immune checkpoint-associated molecules between KRAS mutant and KRAS wild-type groups

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