TY - JOUR AU - Kim-Wanner, Soo-Zin AU - Lee, Seo-Youn AU - Seifried, Erhard AU - Bonig, Halvard PY - 2020 DA - 2020/12/18 TI - Donor-intrinsic variables determine mobilization efficiency: analyses from a cohort of sixty twice-mobilized stem cell donors JO - Journal of Translational Medicine SP - 487 VL - 18 IS - 1 AB - Healthy volunteer registry donors have become the backbone of stem cell transplantation programs. While most registrants will never become actual donors, a small minority are called upon twice, most commonly for the same patient because of poor graft function. Anecdotal evidence provides no hard reasons to disallow second-time mobilized apheresis, but few centers have treated enough two-time donors for definitive conclusions. Moreover, for reasons unknown, the efficiency of G-CSF varies greatly between donations. SN - 1479-5876 UR - https://doi.org/10.1186/s12967-020-02634-z DO - 10.1186/s12967-020-02634-z ID - Kim-Wanner2020 ER -