Table 1 Demographic characteristics and co-morbidity in patients with and without ankylosing spondylitis
Variables | Ankylosing spondylitis | p value | |||
|---|---|---|---|---|---|
No (N = 25,760) | Yes (N = 6440) | ||||
n | % | n | % | ||
Sex | 0.99 | ||||
Male | 12,396 | 48.1 | 3099 | 48.1 | |
Female | 13,364 | 51.9 | 3341 | 51.9 | |
Age, years | 0.99 | ||||
20–34 | 6976 | 27.1 | 1744 | 27.1 | |
35–49 | 7588 | 29.5 | 1897 | 29.5 | |
50–64 | 6592 | 25.6 | 1648 | 25.6 | |
≥ 65 | 4604 | 17.9 | 1151 | 17.9 | |
Mean (SD) † | 47.3 | 17.1 | 47.6 | 16.9 | 0.15 |
Comorbidity | |||||
Diabetes | 1734 | 6.73 | 497 | 7.72 | 0.01 |
Hypertension | 6032 | 23.4 | 1874 | 29.1 | < 0.001 |
Hyperlipidemia | 3857 | 15.0 | 1348 | 20.9 | < 0.001 |
Stroke | 661 | 2.57 | 167 | 2.59 | 0.90 |
Depression | 868 | 3.37 | 375 | 5.82 | < 0.001 |
Coronary artery disease | 2869 | 11.1 | 1054 | 16.4 | < 0.001 |
Head injury | 599 | 2.33 | 209 | 3.25 | < 0.001 |
Chronic kidney disease | 1368 | 5.31 | 532 | 8.26 | < 0.001 |
Epilepsy | 164 | 0.64 | 43 | 0.67 | 0.78 |
Medication | |||||
NSAIDs | 6053 | 23.5 | 1591 | 24.7 | 0.04 |
Immunosuppressant therapy | 1282 | 19.9 | |||
Biological therapy | 37 | 0.57 | |||