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Table 1 Pro-inflammatory cytokines and chemokines significantly suppressed by LMWF5A in LPS-stimulated PBMC

From: LMWF5A suppresses cytokine release by modulating select inflammatory transcription factor activity in stimulated PBMC

Cytokine/chemokine Gene symbol Fold change
C-X-C motif chemokine ligand 9 CXCL9 0.48 ± 0.01
C-X-C motif chemokine ligand 10 CXCL10 0.36 ± 0.15
C-X-C motif chemokine ligand 11 CXCL11 0.58 ± 0.08
Interleukin 1 beta IL1β 0.71 ± 0.05
Interleukin 12 p40 and p70 IL12A and B 0.34 ± 0.07
Tumor necrosis factor alpha TNFA 0.62 ± 0.07
  1. PBMC were exposed to saline or LMWF5A and then stimulated with 100 ng/ml LPS for 24 h. Cytokine release was determined by ELISA array, and data are presented as fold change (OD ± STD, n = 3, p-value =  ≤ 0.05)